Used in neuroscience and biomedical research to quantify aquaporin-4 protein levels in biological samples such as brain tissue homogenates, cerebrospinal fluid, or cell culture supernatants. Helps investigate the role of AQP-4 in water homeostasis, neuroinflammation, and diseases like neuromyelitis optica (NMO), traumatic brain injury, stroke, and epilepsy. Enables researchers to monitor changes in AQP-4 expression under experimental conditions, assess efficacy of therapeutic agents targeting water channel function, and support biomarker development for central nervous system disorders. Suitable for preclinical studies and in vitro analysis, providing a sensitive and specific tool for immunoassay-based detection.