Used in biomedical research to quantify Aquaporin-5 protein levels in tissue extracts, cell lysates, and biological fluids such as saliva and tears. Enables studies on water transport mechanisms in epithelial and glandular tissues. Widely applied in investigating dry eye syndrome, Sjögren's syndrome, and other autoimmune or inflammatory conditions affecting moisture secretion. Supports research in respiratory physiology due to AQP-5 expression in lung alveolar cells. Facilitates biomarker validation and drug development targeting membrane water channels.