Used in biomedical research to quantify levels of protein disulfide isomerase A3 (PDIA3) in cell lysates, tissue extracts, and biological fluids. Enables investigation of PDIA3's role in endoplasmic reticulum stress, unfolded protein response, and protein folding quality control. Commonly applied in studies related to cancer, neurodegenerative diseases, and autoimmune disorders where PDIA3 expression is altered. Supports high-throughput screening and validation of therapeutic targets by providing a reliable, sensitive, and specific measurement method. Also utilized in immunology research to assess PDIA3 involvement in antigen presentation and cell surface signaling.