Used in biomedical research to detect and quantify Aquaporin-4 protein levels in rat tissue samples, particularly in studies related to neuroinflammation and central nervous system disorders. Commonly applied in research on neuromyelitis optica (NMO), where autoantibodies target AQP-4, helping scientists evaluate disease mechanisms and assess therapeutic interventions. The kit enables precise measurement of AQP-4 expression in brain and spinal cord tissues, supporting investigations into water homeostasis, blood-brain barrier integrity, and astrocyte function. Widely utilized in preclinical studies to monitor changes in AQP-4 during injury, infection, or autoimmune responses.