Used in biomedical research to detect and quantify HMGB-1 protein levels in biological samples such as serum, plasma, and cell culture supernatants. This kit is essential for studying inflammation, sepsis, autoimmune diseases, and cancer progression, as HMGB-1 acts as a key mediator in these conditions. It enables researchers to monitor disease activity, evaluate therapeutic responses, and investigate the role of HMGB-1 in cellular processes like apoptosis and immune activation. The ELISA format provides high sensitivity and specificity, making it suitable for both preclinical and clinical research settings.