Used in immunological research to quantify mouse type II collagen (ColⅡ) levels in biological samples such as serum, synovial fluid, or tissue homogenates. Commonly applied in studies of cartilage degradation, osteoarthritis, and autoimmune joint diseases like rheumatoid arthritis. Enables researchers to monitor disease progression, evaluate therapeutic efficacy, and assess biomarkers of extracellular matrix turnover in mouse models. The kit provides a sensitive and specific method for detecting ColⅡ fragments or intact protein, supporting investigation into joint health and repair mechanisms.