Used in immunological research to measure total complement activity in guinea pig serum samples. The kit enables quantification of the CH50 (complement hemolytic 50%) level, which reflects the functional integrity of the classical complement pathway. It is commonly applied in studies involving inflammation, immune response evaluation, and autoimmune diseases in guinea pig models. Researchers use it to assess how experimental treatments, infections, or genetic modifications affect complement system function. The assay is also useful in vaccine development and testing, where complement activation plays a critical role in immune defense mechanisms.