Used in biomedical research to quantitatively measure human Type IV collagen levels in biological samples such as serum, plasma, and tissue homogenates. This kit is particularly valuable in studies related to basement membrane integrity, liver fibrosis, kidney diseases, and cancer metastasis, where Type IV collagen degradation or overproduction is a key biomarker. The assay helps researchers assess extracellular matrix remodeling and evaluate the progression or treatment response in fibrotic and inflammatory conditions.