Used in immunological research to measure total complement activity in biological samples. Helps assess the functional integrity of the classical complement pathway, which is essential in studying immune system responses. Commonly applied in preclinical and clinical studies involving autoimmune diseases, inflammatory conditions, and infectious diseases to evaluate complement system involvement. Also utilized in monitoring disease progression and therapeutic efficacy in models where complement activation plays a key role. Suitable for serum and plasma samples from non-human primates, making it valuable in translational research and vaccine development.