Used in immunological research to quantify levels of C4b-binding protein alpha chain in biological samples. Helps assess complement system activity, particularly in studies related to autoimmune diseases such as systemic lupus erythematosus (SLE), where complement dysregulation plays a key role. Enables researchers to monitor disease progression and evaluate therapeutic interventions targeting the complement pathway. Commonly used in preclinical studies involving rat models to understand inflammation, immune complex clearance, and thrombotic regulation. Provides a reliable, sensitive method for detecting changes in C4BPα concentrations in serum or plasma.