Used in biomedical research to detect and quantify desmoglein-3 (Dsg-3) antibodies in human serum or plasma samples. Plays a critical role in diagnosing and monitoring pemphigus vulgaris, an autoimmune blistering disease where autoantibodies target Dsg-3. The kit enables researchers and clinicians to assess antibody levels, aiding in disease detection, evaluating treatment response, and studying disease progression. Commonly used in clinical laboratories, immunology research, and drug development studies focused on autoimmune dermatological conditions.