Used in biomedical research to quantify desmoglein-1 levels in tissue or fluid samples, aiding in the study of autoimmune skin disorders such as pemphigus vulgaris and pemphigus foliaceus. Helps researchers assess epidermal integrity and monitor disease progression or response to treatment by measuring specific antibody interactions. Widely applied in dermatology research and clinical laboratories for high-sensitivity detection of cell adhesion molecule disruption.