Used in biomedical research to quantify E-cadherin protein levels in cell lysates or tissue samples. Helps assess epithelial cell adhesion integrity, study epithelial-to-mesenchymal transition (EMT) in cancer progression, and evaluate tissue damage or inflammation in experimental models. Commonly applied in oncology, developmental biology, and toxicology studies where changes in cell adhesion play a critical role. Provides a sensitive and specific measurement of soluble or membrane-bound E-cadherin, enabling researchers to monitor disease mechanisms or treatment effects in vitro and in vivo.