Used in biomedical research to quantify E-selectin levels in cell culture supernatants, serum, and plasma. Helps assess endothelial activation and inflammation in studies related to atherosclerosis, sepsis, rheumatoid arthritis, and other inflammatory diseases. Commonly applied in drug development to monitor the effect of anti-inflammatory compounds on endothelial cell function. Also used in clinical research to investigate the role of adhesion molecules in cancer metastasis and leukocyte recruitment.