Used in biomedical research to quantify E-cadherin protein levels in cell lysates, tissue extracts, and biological fluids. Enables assessment of epithelial integrity and cell adhesion in studies related to cancer progression, especially epithelial-to-mesenchymal transition (EMT). Widely applied in oncology, developmental biology, and toxicology to monitor changes in E-cadherin expression associated with tumor invasion, metastasis, and tissue differentiation. Supports high-throughput screening and validation of experimental therapeutics targeting cell adhesion pathways.