Used in biomedical research to quantify GDF-15 levels in biological samples such as serum, plasma, and cell culture supernatants. Helps in studying chronic diseases including cancer, cardiovascular disorders, and metabolic syndromes, where GDF-15 is often elevated. Supports investigation into appetite regulation and body weight control due to GDF-15's role in signaling through the brainstem. Enables researchers to evaluate disease progression, assess therapeutic responses, and discover biomarkers in clinical and preclinical studies.