Used in biomedical research to quantify protein kinase G-II (PKG-II) levels in rat tissue samples or cell lysates. Enables researchers to study the role of PKG-II in cellular signaling pathways, particularly in processes involving cyclic GMP, such as smooth muscle relaxation, bone formation, and renal function. Commonly applied in studies related to cardiovascular diseases, osteoporosis, and kidney disorders. The ELISA format allows for high sensitivity and specificity, making it suitable for detecting low-abundance PKG-II in complex biological samples. Facilitates comparative analysis between experimental groups in preclinical studies.