Used in biomedical research to quantify hypoxia inducible factor-2 (HIF-2) levels in cell or tissue samples. Helps study cellular responses to low oxygen conditions, particularly in cancer research, where tumor hypoxia influences progression and treatment resistance. Supports investigation into diseases involving abnormal HIF-2 activation, such as renal cell carcinoma and polycythemia. Enables evaluation of drug effects on HIF-2 signaling pathways in preclinical studies.