Used in biomedical research to quantify heparan sulfate levels in biological samples such as serum, plasma, and cell culture supernatants. Enables assessment of extracellular matrix remodeling and glycosaminoglycan metabolism in diseases like cancer, inflammation, and kidney disorders. Supports studies on heparanase enzyme activity and its role in tumor metastasis and angiogenesis. Facilitates drug development and evaluation of therapeutic agents targeting heparan sulfate pathways.