Used in immunological research to detect and quantify human immunoglobulin heavy chain variable region (IgHV) in biological samples. Commonly applied in studies related to B-cell development, autoimmune diseases, and B-cell malignancies such as chronic lymphocytic leukemia (CLL). Helps researchers assess IgHV expression levels, evaluate clonality, and monitor disease progression or response to therapy. Widely used in clinical labs and biomedical research for profiling antibody diversity and immune responses.