Used in biomedical research to quantify Human Type II Collagen Fibril Alpha Gene (COL22A1) expression levels in tissue samples and cell cultures. Helps in studying extracellular matrix formation, connective tissue development, and cartilage-related diseases such as osteoarthritis and rheumatoid arthritis. Supports investigation into collagen biosynthesis pathways and tissue engineering applications involving cartilage repair. Also utilized in clinical research to assess biomarkers associated with musculoskeletal disorders and fibrotic conditions.