Used in immunological research to quantify soluble intercellular adhesion molecule 1 (sICAM-1) in biological samples such as serum, plasma, or cell culture supernatants. Helps assess immune activation and inflammation in experimental models involving monkeys. Commonly applied in studies of infectious diseases, autoimmune conditions, and neuroinflammatory disorders to monitor endothelial activation and disease progression. Provides a reliable tool for evaluating the efficacy of therapeutic interventions targeting inflammatory pathways in preclinical research.