Used in immunological research to detect and quantify levels of melanoma differentiation-associated protein 5 (MDA5) in biological samples. Widely applied in studies related to autoimmune diseases such as dermatomyositis and systemic lupus erythematosus, where MDA5 acts as an autoantigen. Helps assess interferon pathway activation, as MDA5 is a key sensor in antiviral innate immunity. Commonly used in clinical research settings to investigate viral infections, cancer immunology, and inflammatory conditions. Enables researchers to monitor disease progression and evaluate therapeutic responses in autoimmune and antiviral studies.