Used in biomedical research to detect and quantify periostin levels in biological samples such as serum, plasma, and tissue lysates. Widely applied in studies related to tissue remodeling, asthma, allergic inflammation, and fibrosis. Also utilized in cancer research, particularly in understanding tumor microenvironment and metastasis, as periostin is associated with epithelial-mesenchymal transition. Supports investigation in cardiovascular diseases, including valve calcification and myocardial repair. Commonly used in preclinical studies and biomarker validation due to its high sensitivity and specificity.