Used in biomedical research to measure levels of the ST2 protein in serum, plasma, or tissue samples. Helps assess inflammatory responses and is particularly valuable in studies related to cardiovascular diseases, such as heart failure, where ST2 acts as a biomarker for cardiac stress and fibrosis. Also applied in immunology research to investigate the IL-33/ST2 signaling pathway involved in allergic inflammation, asthma, and autoimmune disorders. Enables researchers to evaluate disease progression and response to therapy in clinical and preclinical settings.