Used in biomedical research to measure soluble ST2 protein levels in human serum or plasma samples. Helps assess inflammatory responses and is commonly applied in studies related to cardiovascular diseases, such as heart failure, where elevated sST2 levels correlate with disease severity and prognosis. Also utilized in immunology research to investigate the role of the IL-33/ST2 signaling pathway in asthma, allergies, and autoimmune disorders. Enables researchers to evaluate patient risk stratification and monitor therapeutic outcomes in clinical and preclinical settings.