Used in research settings to quantify the levels of thrombin-thrombomodulin complex in biological samples, this ELISA kit helps investigate coagulation processes and endothelial cell activation. It is particularly useful in studies related to thrombosis, disseminated intravascular coagulation (DIC), and other conditions involving abnormal blood clotting. The assay enables detection of the complex formed when thrombin binds to thrombomodulin, a key regulatory step in the anticoagulant pathway. Researchers use this kit to assess vascular injury, monitor disease progression in sepsis or inflammation, and evaluate potential therapeutic interventions targeting the coagulation cascade. Due to its specificity, it supports mechanistic studies in hemostasis and thrombosis without cross-reactivity to individual components like free thrombin or thrombomodulin.