Used in biomedical research to measure levels of transcobalamin II (TCN2), a key protein responsible for transporting vitamin B12 (cobalamin) into cells. This ELISA kit enables researchers to quantify TCN2 in serum, plasma, or cell culture samples, supporting studies on vitamin B12 metabolism, deficiency disorders, cardiovascular health, and neurological conditions. It is widely applied in clinical laboratories and research settings to assess functional vitamin B12 status, as TCN2-bound cobalamin represents the fraction available for cellular uptake. The assay supports investigation into conditions such as hyperhomocysteinemia, pernicious anemia, and cognitive decline, where B12 transport and utilization are impaired.