Used in biomedical research to quantify soluble tumor necrosis factor receptor I (sTNF-RI) levels in biological samples such as serum, plasma, or cell culture supernatants. This ELISA kit enables researchers to study inflammatory processes, immune system regulation, and disease mechanisms related to TNF signaling, including autoimmune diseases like rheumatoid arthritis, sepsis, and chronic inflammatory conditions. It is also employed in preclinical drug development to assess the efficacy of anti-inflammatory therapeutics that modulate the TNF pathway. The assay provides a sensitive and specific means to monitor changes in sTNF-RI concentration under experimental or clinical conditions.