Used in biomedical research to quantify levels of vascular endothelial cadherin in cell culture supernatants, tissue lysates, and biological fluids. Helps assess endothelial cell integrity and vascular permeability in studies related to inflammation, angiogenesis, and vascular diseases. Widely applied in preclinical research on cancer metastasis, atherosclerosis, and diabetic complications to monitor disruption or stabilization of endothelial junctions. Supports evaluation of drug effects on vascular barrier function in vitro and in animal models.