Used in biomedical research to quantify levels of human collagen type XVIII alpha-1 chain in tissue extracts, cell culture supernatants, or biological fluids. This ELISA kit supports studies on extracellular matrix composition, angiogenesis, and tissue development. It is particularly valuable in cancer research, as collagen XVIII and its cleavage product, endostatin, play roles in inhibiting tumor vascularization. Researchers also use it to investigate liver fibrosis, ocular diseases, and developmental disorders linked to basement membrane abnormalities. The assay enables high-sensitivity detection, allowing precise measurement in small sample volumes, making it suitable for longitudinal and preclinical studies.