AX-024 hydrochloride is primarily investigated for its potential therapeutic applications in the field of immunology and autoimmune diseases. It functions as a modulator of T-cell activation, specifically targeting the Nck SH3 domain interaction, which plays a critical role in immune signaling pathways. By inhibiting this interaction, AX-024 hydrochloride has shown promise in reducing excessive immune responses, making it a candidate for treating conditions such as rheumatoid arthritis, lupus, and other autoimmune disorders. Preclinical studies suggest that it may help restore immune balance without causing widespread immunosuppression. Additionally, its mechanism of action is being explored for potential use in organ transplantation to minimize rejection risks. Further research is ongoing to evaluate its efficacy and safety in clinical settings.