Peptide T is a synthetic octapeptide with the amino acid sequence Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr (ASTTTNYT), derived from the V2 loop of the HIV-1 gp120 envelope protein. It is primarily studied for its potential therapeutic applications, particularly in the field of neurology and immunology. It has been investigated for its ability to modulate the immune system, inhibit HIV viral entry by binding to the CXCR4 receptor, and its potential role in treating conditions such as HIV/AIDS. Research suggests that it may help in reducing neuroinflammation and improving cognitive function in patients with HIV-associated neurocognitive disorders. Additionally, Peptide T is explored for its potential to alleviate symptoms of chronic fatigue syndrome and fibromyalgia due to its interaction with the immune system and its anti-inflammatory properties. Its ability to bind to specific receptors in the brain also makes it a candidate for further research in treating other neurological and inflammatory conditions. Note that clinical development has been limited, and it remains primarily a research tool.