Gusperimus trihydrochloride is primarily used in the field of medicine, particularly as an immunosuppressive agent. It is often employed to prevent organ transplant rejection by inhibiting the proliferation of T-cells, which play a key role in immune responses. This helps reduce the risk of the body attacking the transplanted organ. Additionally, it has been explored for treating autoimmune diseases, such as rheumatoid arthritis, by modulating the immune system to prevent it from attacking the body's own tissues. Its application is carefully monitored due to its potent effects on the immune system, requiring precise dosing to balance efficacy and safety.