Carbamicacid,N-[(1R)-1-methyl-2-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-4-yl]ethyl]-,1,1-dimethylethylester
98%
Reagent
Code: #166213
CAS Number
2222846-04-8
blur_circular Chemical Specifications
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Molecular Information
Weight
359.46 g/mol
Formula
C₂₀H₂₉N₃O₃
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
This compound serves as a protected intermediate in pharmaceutical synthesis, particularly for producing kinase inhibitors in targeted cancer therapies. It incorporates a 1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-4-yl core, where the THP group protects the indazole nitrogen to improve handling and selectivity. The side chain features a Boc-protected amine (tert-butoxycarbonyl group), which enhances synthetic stability and can be deprotected post-reaction. This structure facilitates selective enzyme binding and modulation of cellular signaling pathways, making it essential in research for enhancing drug potency, solubility, and metabolic stability.
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