1-Methylindole is widely used in the fragrance and flavor industry due to its strong, earthy, and animalic odor. It is often incorporated into perfumes and colognes to add depth and complexity, particularly in creating musky or leathery notes. Additionally, it serves as a key intermediate in the synthesis of various pharmaceuticals, including compounds with potential anti-inflammatory and anticancer properties. In research, it is utilized as a building block for developing indole-based derivatives, which are explored for their biological activities. Its applications also extend to agrochemicals, where it is used in the production of certain pesticides and herbicides.