Ethyl 5-chloroindole-2-carboxylate is primarily utilized in organic synthesis as a key intermediate for the development of more complex chemical compounds. Its structure is particularly valuable in the pharmaceutical industry, where it serves as a building block for the synthesis of various indole-based drugs. These drugs often target neurological and psychiatric disorders due to the indole moiety's resemblance to neurotransmitters like serotonin. Additionally, this compound is employed in the research and development of agrochemicals, contributing to the creation of novel pesticides and herbicides. Its versatility in chemical reactions, such as coupling and substitution, makes it a crucial component in the synthesis of biologically active molecules.