4-Bromo-1-(tert-butyldimethylsilyl)-1H-indole
98%
Reagent
Code: #141035
CAS Number
193694-04-1
blur_circular Chemical Specifications
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Molecular Information
Weight
310.31 g/mol
Formula
C₁₄H₂₀BrNSi
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Registry Numbers
MDL Number
MFCD07787363
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Physical Properties
Boiling Point
293.0±22.0 °C(Predicted)
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Storage & Handling
Density
1.17±0.1 g/cm3(Predicted)
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of indole-based drug candidates. Its protected indole structure allows selective functionalization at other reactive sites during multi-step organic syntheses. Commonly employed in the preparation of serotonin receptor modulators and kinase inhibitors. The silyl protecting group enhances stability and solubility in organic solvents, facilitating purification and handling in air- and moisture-sensitive reactions. Widely applied in medicinal chemistry research for constructing complex heterocyclic systems.
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