7-Bromo-4-fluoro-1H-indole
98%
Reagent
Code: #145367
CAS Number
292636-09-0
blur_circular Chemical Specifications
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Molecular Information
Weight
214.03 g/mol
Formula
C₈H₅BrFN
thermostat
Physical Properties
Boiling Point
314.2°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of serotonin receptor modulators and other central nervous system (CNS) active compounds. Its structure serves as a building block for creating indole-based bioactive molecules. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the presence of halogen substituents that allow further functionalization via cross-coupling reactions like Suzuki or Buchwald-Hartwig. Also utilized in the preparation of fluorescent probes and imaging agents owing to the indole core’s favorable photophysical properties.
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