1-Boc-3-Hydroxymethylindole
97%
Reagent
Code: #145665
CAS Number
96551-22-3
blur_circular Chemical Specifications
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Molecular Information
Weight
247.29 g/mol
Formula
C₁₄H₁₇NO₃
thermostat
Physical Properties
Boiling Point
396°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used in the synthesis of pharmaceutical intermediates, particularly in the development of serotonin receptor modulators and other neuroactive compounds. Its protected indole structure with a hydroxymethyl group allows selective functionalization, making it valuable in constructing complex indole-based drug candidates. Commonly employed in medicinal chemistry for building blocks in tryptamine and ergot alkaloid analogs. Also utilized in the preparation of kinase inhibitors and anti-migraine agents. The Boc-protected amine ensures stability during multi-step reactions, enabling efficient coupling and derivatization under mild conditions.
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