tert-Butyl 5-cyano-3-iodo-1H-indole-1-carboxylate
98%
Reagent
Code: #145912
CAS Number
864685-26-7
blur_circular Chemical Specifications
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Molecular Information
Weight
368.17 g/mol
Formula
C₁₄H₁₃IN₂O₂
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Registry Numbers
MDL Number
MFCD05864767
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research targeting kinase inhibitors and serotonin receptor modulators. The presence of the cyano and iodo functional groups allows for further transformations via cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling rapid diversification of molecular structure. The tert-butyl carboxylate group acts as a protecting group for the indole nitrogen, offering stability during reactions and can be removed under mild acidic conditions when needed. This compound is valuable in medicinal chemistry for constructing complex indole-based scaffolds found in drug candidates.
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