tert-Butyl 3-bromo-5-nitro-1H-indole-1-carboxylate

98%

Reagent Code: #152267
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CAS Number 914349-31-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.16 g/mol
Formula C₁₃H₁₃BrN₂O₄
badge Registry Numbers
MDL Number MFCD05864776
thermostat Physical Properties
Boiling Point 441.601 °C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of indole-based bioactive molecules. This N-protected derivative features a tert-butoxycarbonyl (Boc) group on the indole nitrogen, which prevents unwanted side reactions during synthesis and can be easily removed under mild acidic conditions. The bromo substituent at position 3 and nitro group at position 5 enable further chemical modifications, such as cross-coupling reactions (e.g., Suzuki-Miyaura) and reductions, making it valuable in constructing complex heterocyclic systems. Commonly employed in medicinal chemistry for creating potential kinase inhibitors and anti-inflammatory agents. Also utilized in research settings to develop fluorescent probes and functionalized indole derivatives for biological studies.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,410.00
inventory 1g
10-20 days ฿7,290.00
inventory 5g
10-20 days ฿31,650.00

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