(3Z)-3-(Phenylmethylidene)-2,3-dihydro-1H-indol-2-one
95%
Reagent
Code: #246316
Alias
(3Z)-3-benzylidene-1H-indole-2-one
CAS Number
23772-61-4
science Other reagents with same CAS 23772-61-4
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Molecular Information
Weight
221.254 g/mol
Formula
C₁₅H₁₁NO
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Registry Numbers
MDL Number
MFCD00158610
thermostat
Physical Properties
Melting Point
168-169 °C
Boiling Point
438.0±45.0 °C
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Storage & Handling
Density
1.237±0.06 g/cm3
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Shows potential in targeting tyrosine kinases involved in tumor growth and angiogenesis. Also investigated for anti-inflammatory and neuroprotective properties in preclinical studies. Serves as a scaffold in medicinal chemistry for optimizing drug candidates due to its planar structure and ability to form hydrogen bonds.
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