Ethyl indolizine-1-carboxylate is primarily utilized in organic synthesis as a key intermediate for the development of more complex chemical compounds. Its structure is valuable in the synthesis of heterocyclic compounds, which are often explored for their potential pharmacological activities. Researchers use it to create derivatives that may exhibit biological properties, such as antimicrobial, anti-inflammatory, or anticancer effects. Additionally, it serves as a building block in the preparation of dyes, agrochemicals, and other specialty chemicals. Its versatility in chemical reactions makes it a useful tool in medicinal chemistry and material science research.