XEN445 is primarily used in research settings as a selective modulator of specific cellular pathways involved in inflammation and immune response. It shows potential in preclinical studies for targeting overactive immune cells without broadly suppressing the entire immune system. This makes it a candidate for investigating chronic inflammatory conditions such as rheumatoid arthritis and inflammatory bowel disease. Its mechanism allows for fine-tuned control in cellular signaling, which is valuable in developing targeted therapies. Additionally, XEN445 is utilized in pharmacological studies to help map pathway interactions and assess therapeutic windows for related drug candidates. Due to its experimental status, it remains restricted to laboratory and non-clinical use.