1-(Difluoromethyl)-3-iodobicyclo[1.1.1]pentane
98%
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This compound is primarily utilized in the field of organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique bicyclo[1.1.1]pentane structure, combined with difluoromethyl and iodine substituents, makes it a valuable building block for creating complex molecules. It is often employed in cross-coupling reactions, such as Suzuki or Sonogashira couplings, to introduce the bicyclo[1.1.1]pentane moiety into target compounds. This moiety is known to enhance metabolic stability and improve pharmacokinetic properties in drug candidates. Additionally, the compound is used in medicinal chemistry research to explore novel drug scaffolds, especially for central nervous system (CNS) targets, due to its ability to mimic phenyl rings while offering distinct physicochemical properties. Its applications also extend to materials science, where it can be incorporated into polymers or small molecules to modify their electronic or structural characteristics.
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