PPADS tetrasodium is widely used in research as a selective antagonist for P2X purinergic receptors. These receptors are involved in various physiological processes, including neurotransmission, inflammation, and pain signaling. By blocking these receptors, PPADS tetrasodium helps scientists study the role of ATP and other nucleotides in cellular communication. It is particularly valuable in neuroscience and pharmacology for understanding mechanisms underlying pain, inflammation, and neurodegenerative diseases. Additionally, it aids in exploring potential therapeutic targets for conditions like chronic pain and inflammatory disorders. Its application extends to in vitro and in vivo studies, providing insights into receptor function and signaling pathways.