Used in research settings to study thermoregulation and heat sensitivity in neuronal pathways, particularly related to transient receptor potential (TRP) channels. Shows selectivity toward TRPV1 and TRPV3 receptors, making it a tool compound for investigating pain signaling and skin barrier function. Also applied in preclinical models to explore inflammatory responses and neurogenic inflammation. Due to its modulatory effects on sensory neurons, it is utilized in the development of topical analgesics and dermatological treatments targeting itch and irritation. Not intended for therapeutic use in humans at this stage.