NMDAR antagonist 1 is primarily used in neuroscience research to study the role of NMDA receptors in brain function. It helps in understanding conditions like Alzheimer's disease, epilepsy, and chronic pain by blocking NMDA receptor activity. This compound is also utilized in experimental models to explore neuroprotection and synaptic plasticity, providing insights into potential therapeutic strategies for neurological disorders. Additionally, it aids in investigating the mechanisms of excitotoxicity, which is linked to stroke and traumatic brain injury.