Ferric Pyrophosphate

Ferric Pyrophosphate
  • Product Code: 127635

Effective treatment of iron deficiency anemia

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Test Name Specification
Sensory index Yellow-white to yellow-brown powder Slightly irony
Identification test Pass the test
Iron assay, ω/% 24.0-26.0
Loss on ignition, ω/% ≤20.0
Lead (mg/kg) ≤4.0
Arsenic (mg/kg) ≤3.0
Total mercury (mg/kg) ≤3.0
Chloride, ω/% ≤3.55

  • Effective treatment of iron deficiency anemia: Ferric pyrophosphate significantly increases hemoglobin and serum ferritin levels, resolving anemia within 30 days and maintaining improvements over 12 weeks in both general and pregnant populations (Srivastav A., Kshirsagar S., Adhav T., Ganu G., Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus 2024;16(3):e57108; Gandhi A., Bhatt H., Patel M., et al. Retrospective observational study to assess clinical impact of Micronized Microencapsulated Ferric Pyrophosphate in antenatal settings of India. Int J Reprod Contracept Obstet Gynecol 2024; DOI:10.18203/2320-1770.ijrcog20242810)

  • Maintains hemoglobin and reduces ESA use in hemodialysis patients: When administered via dialysate, ferric pyrophosphate citrate sustains hemoglobin within target ranges and lowers the need for erythropoiesis-stimulating agents without causing iron overload (Macdougall I.C., et al. Ferric Pyrophosphate Citrate Administered via Dialysate Reduces ESA Use and Maintains Hemoglobin in Hemodialysis Patients. Journal of the American Society of Nephrology 2015)

  • Milder gastrointestinal side effects: Compared to conventional ferrous salts, ferric pyrophosphate formulations exhibit reduced gastrointestinal irritation, improving tolerability for long-term supplementation (DrugBank. Ferric Pyrophosphate (DB09147): Mechanism of Action. DrugBank Online 2025)

  • Efficient iron delivery bypassing the reticuloendothelial system: As a soluble compound, ferric pyrophosphate donates iron directly to transferrin, enabling rapid uptake by erythroblasts and avoiding macrophage sequestration (Fishbane S., Singh A.K., et al. Continuous Replacement Using Iron Soluble Equivalents (CRUISE) Trials: Ferric Pyrophosphate Citrate in Hemodialysis Patients. Nephrology Dialysis Transplantation 2014)




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Ferric Pyrophosphate

Effective treatment of iron deficiency anemia

  • Effective treatment of iron deficiency anemia: Ferric pyrophosphate significantly increases hemoglobin and serum ferritin levels, resolving anemia within 30 days and maintaining improvements over 12 weeks in both general and pregnant populations (Srivastav A., Kshirsagar S., Adhav T., Ganu G., Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus 2024;16(3):e57108; Gandhi A., Bhatt H., Patel M., et al. Retrospective observational study to assess clinical impact of Micronized Microencapsulated Ferric Pyrophosphate in antenatal settings of India. Int J Reprod Contracept Obstet Gynecol 2024; DOI:10.18203/2320-1770.ijrcog20242810)

  • Maintains hemoglobin and reduces ESA use in hemodialysis patients: When administered via dialysate, ferric pyrophosphate citrate sustains hemoglobin within target ranges and lowers the need for erythropoiesis-stimulating agents without causing iron overload (Macdougall I.C., et al. Ferric Pyrophosphate Citrate Administered via Dialysate Reduces ESA Use and Maintains Hemoglobin in Hemodialysis Patients. Journal of the American Society of Nephrology 2015)

  • Milder gastrointestinal side effects: Compared to conventional ferrous salts, ferric pyrophosphate formulations exhibit reduced gastrointestinal irritation, improving tolerability for long-term supplementation (DrugBank. Ferric Pyrophosphate (DB09147): Mechanism of Action. DrugBank Online 2025)

  • Efficient iron delivery bypassing the reticuloendothelial system: As a soluble compound, ferric pyrophosphate donates iron directly to transferrin, enabling rapid uptake by erythroblasts and avoiding macrophage sequestration (Fishbane S., Singh A.K., et al. Continuous Replacement Using Iron Soluble Equivalents (CRUISE) Trials: Ferric Pyrophosphate Citrate in Hemodialysis Patients. Nephrology Dialysis Transplantation 2014)

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